Common Laboratory Animals and Handling Techniques Anuja.M.K. and you may need to create a new Wiley Online Library account. Techniques for performing parenteral injections and blood collection are addressed by separate Animal Care Services (ACS) guidelines. The importance of laboratory animals being habituated to handling early on, and the fact that even simple manipulations can cause stress if the animals are not used to handling, has been known and recommended for a long time (Kvetnansky . 18.12.5 Animal Handling. Generally, slow and deliberate movements should be used around animals. They are safe, reliable, economical, efficient, and ensure that the mouse strains produced are genetically well-defined. Room order entry 3. A single mother with 11 pups was cap\൴ured near Aleppo, Syria, on April 12, 1930, by an Israeli professor in search of a different species of hamster to use in resea對rch on leishmaniasis. Use of Laboratory Animals in Biomedical and Behavioral Research (1988) Animals for Research: A Directory of Sources, Tenth Edition and Supplement (1979) Amphibians: Guidelines for the Breeding, Care and Management of Laboratory Animals (1974) Copies of these reports may be ordered from the National Academies Press (800) 624-6242 or (202) 334-3313 Handling and Restraint of Small Laboratory Animals These guidelines have been developed to introduce investigative staff to procedures recommended for handling and restraint of small laboratory animals. Labelling of the cages 7. Handbook of laboratory animal … The exact procedure for rodent breeding for investigators is performed according to instructions in the individual animal use protocols. •Handling •Behavior •Diseases •Uses in research. The Golden or Syrian Hamster. An important requirement for laboratory animals (a part from price) is that they should be easy to keep. History . Search for more papers by this author. Learn about our remote access options. Food and bedding stores should be clean and dry; food stores should be vermin proof, insect proof, cool and sunless. The detection of signs of disease in animals 4. Under normal conditions, all standard laboratory animals, excepting primates, should be handled with bare hands. et al., 1978; Maurer . Animal handling techniques should be taught to inexperienced workers and used consistently by everyone. vii . Handling of laboratory animal. Examples of relevant guidelines include the Guidelines for adequate veterinary care (American College of Laboratory Animal ... appropriate procedures are implemented for quarantining and handling animals that pose a risk to other animals and to humans because of naturally acquired or experimentally induced infectious disease. However, research has shown that handling of animals with forceps is associated with a higher incidence of repetitive motion injuries in animal care and use personnel. Please check your email for instructions on resetting your password. ... Having a Veterinarian in IAEC is mandatory for judging level of care and handling of Laboratory animals in a given protocol. means you agree to our use of cookies. Main Nominee (01) ... MD/ MS with research experience in laboratory animal handling. In all cases only the minimal amount of force necessary should be employed. Current Protocols Essential Laboratory Techniques; Current Protocols in Food Analytical Chemistry; Current Protocols in Human Genetics; ... Care and Handling of Laboratory Animals. Insect pests 4. Find out more about this exciting new development, Using our new visualization tools you can, Using our new highlighting and annotation tool you can, remove selected records that are not saved in My CABI, sign you out of your Litter 5. Use the link below to share a full-text version of this article with your friends and colleagues. M pharm part 1 Pharmacology Contents: Contents Introduction Types of experimental animals used Animal handling Routes of drug administration in experimental animals Blood collection from experimental animals Conclusion References This book discusses common laboratory species individually with reference to anatomy, reproduction, maintenance, methods of handling, and identification. These techniques have been developed and used by The Jackson Laboratory for nearly 80 years. Handling: Animals should be handled with care. Workers should approach animals from the front and avoid their blind spots and the “kick zone” behind cattle and horses. A. Animal handling requires proper care for which only technical personnel are hired. Back to top. Laboratory animals are inevitably subjected to human contact throughout their lives, during both husbandry and experiments. drugs, equipment, feed, bedding) should be described in the format “generic description (trade name, vendor name, city and country where vendor located)". (2000) Introduction to the principles of animal care and use. Taking the Animal Care and Handling course and receiving a certificate for successful completion of the course does not satisfy all of the regulatory requirements of other City and State Agencies. Marking animals 12. 2. Amphibians: Guidelines for the Breeding, Care and Management of Laboratory Animals (1974) Copies of these reports may be ordered from the National Academies Press (800) 624-6242 or (202) 334-3313 www.nap.edu . 1978 No.2nd edition pp.xii + 211pp. Science Education (Basic Biology) Fundamentals of Breeding and Weaning. Breeding of and Experiments on Animals (Control and Supervision) Rules, 1998 36 -41 ... Having a Veterinarian in IAEC is mandatory for judging level of care and handling of Laboratory animals in a given protocol. Perishable foods should be stored in cold rooms, refrigerators or freezers. View the article PDF and any associated supplements and figures for a period of 48 hours. This is reflected in its behaviour and, when Rodent Handling and Restraint Techniques. B.Nominees from the CPCSEA: i. Sudden movements are never a good idea, regardless of the species or breed involved. If you have previously obtained access with your personal account, please log in. Although little scientific information on handling and restraint of mice is available, many general text books touch upon the technical approach of this topic. Cages 6. Lab animal care: guidelines to good practice in housing and. New workers and researchers should be supervised by animal care staff until they have demonstrated their ability to work with the animals without damage or stress to the animal itself and to themselves. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities—a resource of proven value, now updated and expanded. Science Education (Basic Biology) Rodent Identification II. This fourth edition retains all the classic features that have made it a must-have reference including emphasis on best practice in order to improve animal welfare. Scientist from outside the Institute (01) iv. Link Nominee * iii. The rabbit is picked up from cage with the ears by one hand in a firm grip and another hand is placed under the hind-quarters to support the weight and then lifted gently. A NOTE ON THE BREEDING OF GUINEA-PIGS WITHOUT FRESH GREEN FOOD BY H. M. BRUCE From the National Institute for Medical Research, London, N.W. Refer to your Institutional Animal Care and Use Committee and/or facility guidelines for handling practices. Class participants have the opportunity to practice their newly-acquired skills under the supervision of experienced trainers. This card records the breeding of 1-2 female rodents per cage. The most common laboratory hamster is the Golden or Syrian hamster, Mesocricetus auratus. Therefore, laboratory animal handling, care and its management is an integral part of any research laboratories, especially laboratories of animal research institutes. The greater part of the book consists of fifteen sections, each dealing with the care, breeding and diseases of a single species (or group of related species). It was a privilege to be involved in this project. CAB Direct provides B.Nominees from the CPCSEA: i. Individuals were transferred from the traditional barren single-cages to compatible pair-housing arrangements in double-cages furnished with perches, gnawing sticks and custom-made food puzzles. each person handling the bird to advance basic and/or clinical principles to improve health care for all birds. This bestseller has been an essential book for all those working with laboratory animals since it was first published in 1994. Refinement techniques were developed for caged research rhesus macaques (Macaca mulatta) in order to better foster the animals' behavioral health and well-being. a convenient, single point of access to all of your CABI database subscriptions. Laboratory personnel must wear laboratory coats when working with animals in the vivarium. Principles, minimum standards and recommendations for the housing and care of laboratory mice, rats, guinea pigs and rabbits Part 3.1 — Nutrition Part 3.2 — Animal enclosures Part 3.3 — Climate control Part 3.4 — Behaviour and environmental enrichment Part 3.5 — Maintenance and hygiene Part 3.6 — Handling and basic procedures Take care to avoid blind spots and approach animals slowly so that they are always aware of your presence. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, By continuing to browse this site, you agree to its use of cookies as described in our, Current Protocols Essential Laboratory Techniques, Current Protocols in Food Analytical Chemistry, Current Protocols in Magnetic Resonance Imaging, Current Protocols in Nucleic Acid Chemistry, I have read and accept the Wiley Online Library Terms and Conditions of Use, https://doi.org/10.1002/0471142735.im0100s14. Individual training sessions can also be arranged. Breeding cage cards should be filled out completely. Use of room cards on the doors of animal rooms indicating the species is a good practice. Institutions should employ people trained in laboratory animal science or provide for both formal and on the job training to ensure effective implementation of the programm. incorporating the leading bibliographic databases CAB Abstracts and Global Health. Use of Laboratory Animals in Biomedical and Behavioral Research (1988) Animals for Research: A Directory of Sources, Tenth Edition and Supplement (1979) Amphibians: Guidelines for the Breeding, Care and Management of Laboratory Animals (1974) Copies of these reports may be ordered from the National Academies Press (800) 624-6242 or (202) 334-3313 session so others can sign in. Prevention of disease 3. et al., 2008). CAB Direct The breeding, care and management of experimental animals. There are over 13,714,000 records available in CAB Direct | Last updated on January 23, 2021. Common laboratory animal and handling techniques. ... o Handling of laboratory animals o Breeding and housing practices in laboratory animals Laboratory animal breeding: Breeding techniques of different species of laboratory animals, inbreeding and out breeding, breeding and management of transgenic, knockouts and other genetically modified animal models Basic experimental animal techniques: Animal handling and … * Addressing Breeding Problems in Mice ... Physiological Effects of Animal Handling and Housing (Free to members.) LABORATORY ANIMAL HANDLING-CARE AND FACILITY 11 A ... age and weight, breed and type, color and marking and any physical abnormalities or other identifying features. FAQs (updated May 2020) Please note that this newly restructured FAQ page includes new and revised questions related to the 8th edition of the Guide for the Care and Use of Laboratory Animals (NRC 2011). Talk softly as you approach an animal so it hears you coming. Potential ethical challenges which might confront laboratory animal professionals using rodents and rabbits such as challenges related to breeding colonies, genetically modified rodents, use of animals in cancer research, perinatal animal use, and use of animals in neuroscience and behavioral research have been used as examples. Breeding strategies for maintaining colonies of laboratory mice. Good animal welfare is also dependent on timely and accurate care and treatment of laboratory animals to minimize pain and distress. Continuing to use www.cabdirect.org The term also relates to the care that is provided to animals as an aid in managing pain and distress. When handling laboratory animals, gloves should be worn, adequate washing facilities should be provided and prophylactic immunisation against tetanus is strongly recommended. Normally laboratory mice have to be ‘involved’ by means of professional handling/restraint in order to perform all procedures necessary during husbandry and/or experimentation. breeding sites and be continued as part of daily hus-bandry procedures in order to familiarize the animals with people and manipulations. Breeding 11. Virtually all amphibians begin their lives in the water as fully aquatic gill-breathing larvae (tadpoles). Cleanliness 4. Products used (e.g. Extensive online help - available wherever you are in CAB Direct. Showing 1 - 15 in 15 videos. Diet 3. handling or restraining technique will not only elim- nate the risk of physical injury to the animal but will also reduce the level of stress caused by the ma- nipulation. Handling and Restraint 31 c Robert W Kemp Astra Zeneca, Macclesfield, Cheshire, UK Introduction The laboratory rat, like its wild counterpart, is an extremely intelligent animal, probably more so than the other rodents commonly used for biomedical research. Participation is not required, but it is strongly encouraged. Patricia Brown. While this is widely accepted for both the Like most websites we use cookies. Measures to refine experimental techniques to benefit animal welfare can be described in detail and the disposition and fate of the animals at the end of the experiment should be clear. During dissections and post-mortem examinations, gloves, aprons (preferably disposable) and … Maintaining healthy, genetically diverse populations requires strategic management and planning for the individual animals within the breeding population so that visitors can continue to gain a personal appreciation for the species in the care of AZA-accredited institutions for generations to come. 6Department of Pharmacology 7. Learn more. If routine handling procedures are aversive, animals are likely to develop anxiety Temperature and Humidity 9. Fluid 2. ULAM’s standard cage changing practices have required Animal Technicians to use forceps when transferring mice between cages for the past two decades. Health assessments … Barrier housing involves special cages and procedures, like sterilizing the bedding and passing the room air through special filters. The Mouse and Rat Workshops: Hands-on Animal Techniques workshops are three and a half hour sessions that provide investigators with an opportunity to receive training on techniques using live mice and rats.Instructors for these small group sessions are certified laboratory animal technologists and therefore provide a good opportunity for learning basic skills. Roundtable on Science and Welfare in Laboratory Animal Use This roundtable brings together representatives from government, industry, animal advocacy groups, professional societies, and academic institutions to discuss science- and welfare-related issues dealing with the use of animals … Lab Policy Page 4 of 5 Separate stores should be provided for food, bedding, cages, cleaning materials and other items. Without these two pieces of information little genetic change can be made in a pop-ulation. Working off-campus? Search for more papers by this author. Introduction to vivarium, husbandry staff, and supplies 2. Overview of Animal Breeding Fall 2008 1 Required Information Successful animal breeding requires 1. the collection and storage of data on individually identi ed animals; and 2. complete pedigree information about the sire and dam of each animal. It is the business owner's responsibility to apply for all other permits, licenses, and authorizations required by other City and State Agencies. FEEDING AND BREEDING OF LABORATORY ANIMALS XII. H. Animals that reach or exceed their breeding life should be culled from the colony and replaced with offspring reserved for this purpose (It may be necessary to periodically bring in “new blood,” i.e., new animals from other blood lines in order to maintain the viability of the colony). The most important item on a rodent breeding bin is the cage ID/breeding record card. Ular staff members provide animal handling requires proper care for which only technical personnel are hired the... 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Maintaining colonies of laboratory animals ( Control and supervision ) Rules, 1998 care handling and breeding techniques of laboratory animals. Of 48 hours IAEC is mandatory for judging level of care and handling laboratory... Mouse strains produced are genetically well-defined instructions on resetting your password you would like to, you can now your... Handling small mammals and rodents produced are genetically well-defined breeding sites and be continued as part of daily procedures. Minimal amount of force necessary should be provided for food, bedding, cages, materials. Aware of your CABI database subscriptions | Last updated on January 23, 2021 used around animals January,... All those working with laboratory animals since it was first published in 1994, husbandry,. Gnawing sticks and custom-made food puzzles pair-housing arrangements in double-cages furnished with perches, gnawing sticks and food! To familiarize the animals with Caution your Institutional animal care and handling of laboratory.! All standard laboratory animals ( a part from price ) is that they be! Hears you coming... Having a Veterinarian in IAEC is mandatory for judging level of and! In all cases only the minimal amount of force necessary should be easy to keep 2000 ) to! And avoid their blind spots and approach animals slowly so that they should vermin! Rules, 1998 36 -41 4 continued as part of daily hus-bandry procedures in order familiarize! Be easy to keep all animals with Caution Institute ( 01 )... MD/ with...